George L. Sutphin

Principle Investigator

Office: LSS 531
Lab: LSS 503


George L. Sutphin, Ph.D., is an academic scientist at the University of Arizona focused on understanding the molecular basis of aging. He uses a combination of systems and comparative genetics to identify new molecular processes involved in aging and characterize their interaction with known environmental and genetic aging factors. By understanding the basic molecular architecture that underlies the aging process, the goal of Dr. Sutphin’s work is to identify new targets for clinical intervention to extend healthy human lifespan and simultaneously treat or delay onset of multiple disease of aging, such as neurodegeneration, cancer, cardiovascular disease, and diabetes. Dr. Sutphin began his academic career as an engineer, earning a B.S. and M.S. in Aeronautics & Astronautics from the University of Washington in 2004 and 2006, respectively, before developing an interest in the basic biology of aging. He received his Ph.D. in Molecular & Cellular Biology from the University of Washington in 2012 and completed his post-doctoral training at The Jackson Laboratory in 2017. Dr. Sutphin was appointed Assistant Professor in Molecular & Cellular Biology at the University of Arizona in 2018

Dr. Sutphin is an active member of the broader aging research community. During his graduate and postdoctoral tenure he served on the trainee governance board at the Gerontological Society of America (GSA) and is currently a serving member of the Board of Directors of the American Aging Association (AGE). In addition to his primary appointment, he has affiliate appointments in the BIO5 Institute and the Arizona Center on Aging (ACOA) at the University of Arizona.


Research Interests

  • Biology of Aging
  • Molecular Mechanism of Age-Associated Disease
  • Comparative Genetics
  • Systems Genetics
  • Machine Learning
  • Mouse Biology
  • Nematode Biology
  • Yeast Biology